Pharmacokinetics and Optical Administration Method for Oral Etoposide.
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چکیده
منابع مشابه
Effects of quercetin on the pharmacokinetics of Etoposide after oral or intravenous administration of etoposide in rats.
Etoposide [4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene)-beta-D-glucopyranoside] is a substrate for P-glycoprotein (P-gp) and cytochrome P450 (CYP) 3A. This study was designed to investigate the effects of quercetin (3,5,7,3',4'-pentahydroxyflavanone), a P-gp and CYP3A inhibitor, on the pharmacokinetics of etoposide in rats. Etoposide was administered to rats orally (9 mg/kg) or i.v. (3 mg...
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ژورنال
عنوان ژورنال: Japanese Journal of Hospital Pharmacy
سال: 1993
ISSN: 2185-9477,0389-9098
DOI: 10.5649/jjphcs1975.19.119